منابع مشابه
Down-regulation of microRNA-182 and microRNA-183 predicts progression of osteosarcoma
Introduction The aim of this study was to investigate the expression levels of microRNA-182 and microRNA-183 and their association with clinicopathological features in patients with osteosarcoma. Material and methods Total RNA was purified from samples and noncancerous bone tissues and then quantitative real-time polymerase chain reaction was applied to evaluate the expression levels of micro...
متن کاملEffects of microRNAs polymorphism in cancer progression
MicroRNAs (miRNAs) are known as a new class of small RNAs (18-25 nucleotides) that regulate gene expression at multiple levels from transcription to translation. Considering the important role of miRNAs in cell proliferation, differentiation, and apoptosis, any variations in their expression can contribute to various anomalies, such as tumorigenesis. Single-nucleotide polymorphisms (SNPs) have ...
متن کاملExpression and Significance of MicroRNA-183 in Hepatocellular Carcinoma
OBJECTIVE In our previous study, we found that some miRNAs were deregulated in hepatocellular carcinoma (HCC), including miR-183. However, the expression of miR-183 in the progression of benign liver diseases to HCC and its correlation with clinicopathologic factors remain undefined. METHODS MiR-183 expression was measured in normal controls (NC) (n = 21), chronic viral hepatitis B or C (CH) ...
متن کاملSignificance of microRNA-183 family expression in cancer diagnosis: a meta-analysis
Cancer is the third major cause of death in the world and it has turned into an enormous threat to human health. MicroRNAs have been considered as novel and noninvasive biomarkers for human cancer detection. The microRNA-183 (miRNA-183, miR-183) family, consisting of miR-96, miR-182 and miR-183, is considered to be associated with various types of human cancer. However, the diagnostic performan...
متن کاملEvaluation of MicroRNA-99a and MicroRNA-205 Expression Levels in Bladder Cancer
Bladder cancer is the second most common cancer in the genitourinary tract, showing often recurrence and progresse into invasive states. Epigenetic changes, such as microRNA alteration are involved in bladder cancer tumorigenesis through a variety of signaling pathways. The epigenetic state depends on geographic and lifestyle conditions. The aim of this study was to investigate the expression l...
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ژورنال
عنوان ژورنال: Journal of Cancer
سال: 2020
ISSN: 1837-9664
DOI: 10.7150/jca.39044